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Wrinkle Reduction Treatment
Botulinum Toxin Injection
Botulinum Toxin Injection
Botulinum toxin injection, is a non-surgical treatment that temporarily reduces facial wrinkles and fine lines. This precise treatment targets specific facial muscles to create a refreshed appearance.
Botulinum toxin injection, is a non-surgical treatment that temporarily reduces facial wrinkles and fine lines. This precise treatment targets specific facial muscles to create a refreshed appearance.


Botulinum Toxin Center in Istanbul
Botulinum Toxin Center in Istanbul
Dr. CBS performs botulinum toxin injections in Istanbul, Türkiye. This is a precise medical procedure for facial muscle relaxation and wrinkle treatment.
Dr. CBS performs botulinum toxin injections in Istanbul, Türkiye. This is a precise medical procedure for facial muscle relaxation and wrinkle treatment.
Neurotoxin Treatment for Facial Rejuvenation
Neurotoxin Treatment for Facial Rejuvenation
Many people seek non-surgical solutions for dynamic facial wrinkles.
Dynamic wrinkles form from repeated muscle movements during facial expressions. Botulinum toxin precisely targets these muscles, temporarily reducing wrinkle appearance and preventing their deepening over time.

What is Botulinum Toxin Treatment?
Botulinum toxin is a purified protein that temporarily relaxes specific facial muscles. Several FDA-approved neurotoxins are available. The treatment involves precise injections into targeted muscles to reduce wrinkles and prevent their progression.
Treatable Conditions
Forehead and frown lines
Masseter muscle (jaw) enlargement
Crow's feet around eyes
Bunny lines on nose
Gummy smile
Hyperhidrosis (excessive sweating) in underarms, palms, and other areas
Benefits of Botulinum Toxin
Benefits of Botulinum Toxin
Reduced facial wrinkles
Prevention of wrinkle deepening
No downtime needed
Temporary and reversible results
Significant reduction in excessive sweating
How it Works
Book a Free Consultation
Consultation
✔ Assessment of facial muscles ✔ Discussion of treatment goals ✔ Review of medical history ✔ Explanation of expected results ✔ Treatment plan development


Procedure
✔ Clean skin preparation and anesthetic cream ✔ Precise injection mapping ✔ Quick treatment (5-10 minutes) ✔ Minimal discomfort ✔ Immediate return to activities ✔ Specific post-care instructions
Recovery
✔ Initial effects within 3-5 days ✔ Full results at 2 weeks ✔ Results last 4-5 months ✔ Follow-up assessment ✔ Maintenance plan development ✔ Regular treatments for best results

How it Works
Book a Free Consultation
Consultation
✔ Assessment of facial muscles ✔ Discussion of treatment goals ✔ Review of medical history ✔ Explanation of expected results ✔ Treatment plan development


Procedure
✔ Clean skin preparation and anesthetic cream ✔ Precise injection mapping ✔ Quick treatment (5-10 minutes) ✔ Minimal discomfort ✔ Immediate return to activities ✔ Specific post-care instructions
Recovery
✔ Initial effects within 3-5 days ✔ Full results at 2 weeks ✔ Results last 4-5 months ✔ Follow-up assessment ✔ Maintenance plan development ✔ Regular treatments for best results

How it Works
Book a Free Consultation
Consultation
✔ Assessment of facial muscles ✔ Discussion of treatment goals ✔ Review of medical history ✔ Explanation of expected results ✔ Treatment plan development


Procedure
✔ Clean skin preparation and anesthetic cream ✔ Precise injection mapping ✔ Quick treatment (5-10 minutes) ✔ Minimal discomfort ✔ Immediate return to activities ✔ Specific post-care instructions
Recovery
✔ Initial effects within 3-5 days ✔ Full results at 2 weeks ✔ Results last 4-5 months ✔ Follow-up assessment ✔ Maintenance plan development ✔ Regular treatments for best results


Considerations
01.
Results are temporary
02.
Treatment needs repetition
03.
Individual responses vary
04.
Some activities restricted post-treatment
05.
Proper injection technique crucial
06.
Regular maintenance recommended

Considerations
01.
Results are temporary
02.
Treatment needs repetition
03.
Individual responses vary
04.
Some activities restricted post-treatment
05.
Proper injection technique crucial
06.
Regular maintenance recommended

Considerations
01.
Results are temporary
02.
Treatment needs repetition
03.
Individual responses vary
04.
Some activities restricted post-treatment
05.
Proper injection technique crucial
06.
Regular maintenance recommended

Got any question?
What's the difference between brands?
Several approved brands exist, all containing the same active ingredient but in different formulations.
How long do results last?
Results typically last 4-5 months, though this varies by individual and treated area.
Is the treatment painful?
Is the treatment painful?
When will I see results?
Initial changes appear within 3-5 days, with full results visible after 2 weeks.
Can I return to normal activities immediately?
Yes, though certain activities should be avoided for 4-6 hours post-treatment.
How often should I get treatments?
Most patients maintain results with treatments every 5-6 months.
Will my face look frozen?
Proper technique ensures natural movement while reducing wrinkles. The goal is refreshed, not frozen appearance.
Can botulinum toxin prevent wrinkles?
Yes, regular treatments can help prevent wrinkles from deepening over time.
Is there any preparation needed?
Avoid blood thinners and certain supplements for several days before treatment, as directed by your doctor.
What is the cost of treatment in Istanbul?
Contact our clinic for current pricing. Cost varies by treatment areas and units needed.
Got any question?
What's the difference between brands?
Several approved brands exist, all containing the same active ingredient but in different formulations.
How long do results last?
Results typically last 4-5 months, though this varies by individual and treated area.
Is the treatment painful?
Is the treatment painful?
When will I see results?
Initial changes appear within 3-5 days, with full results visible after 2 weeks.
Can I return to normal activities immediately?
Yes, though certain activities should be avoided for 4-6 hours post-treatment.
How often should I get treatments?
Most patients maintain results with treatments every 5-6 months.
Will my face look frozen?
Proper technique ensures natural movement while reducing wrinkles. The goal is refreshed, not frozen appearance.
Can botulinum toxin prevent wrinkles?
Yes, regular treatments can help prevent wrinkles from deepening over time.
Is there any preparation needed?
Avoid blood thinners and certain supplements for several days before treatment, as directed by your doctor.
What is the cost of treatment in Istanbul?
Contact our clinic for current pricing. Cost varies by treatment areas and units needed.
Got any question?
What's the difference between brands?
Several approved brands exist, all containing the same active ingredient but in different formulations.
How long do results last?
Results typically last 4-5 months, though this varies by individual and treated area.
Is the treatment painful?
Is the treatment painful?
When will I see results?
Initial changes appear within 3-5 days, with full results visible after 2 weeks.
Can I return to normal activities immediately?
Yes, though certain activities should be avoided for 4-6 hours post-treatment.
How often should I get treatments?
Most patients maintain results with treatments every 5-6 months.
Will my face look frozen?
Proper technique ensures natural movement while reducing wrinkles. The goal is refreshed, not frozen appearance.
Can botulinum toxin prevent wrinkles?
Yes, regular treatments can help prevent wrinkles from deepening over time.
Is there any preparation needed?
Avoid blood thinners and certain supplements for several days before treatment, as directed by your doctor.
What is the cost of treatment in Istanbul?
Contact our clinic for current pricing. Cost varies by treatment areas and units needed.
A Personal Note from Dr. CBS: Botulinum Toxin Treatment in Istanbul
A Personal Note from Dr. CBS: Botulinum Toxin Treatment in Istanbul
Dr. CBS shares insights on botulinum toxin treatments and achieving natural-looking results.
Dr. CBS shares insights on botulinum toxin treatments and achieving natural-looking results.
Botulinum toxin treatment is a precise medical procedure requiring detailed understanding of facial anatomy and muscle function. Our goal is to provide natural-looking improvement while maintaining normal facial expressions. The key to successful results lies in proper technique and appropriate dosing. Each treatment is customized to your specific facial anatomy and goals, ensuring balanced and harmonious results.

Dr. Cem Berkay Sinaci
Plastic Surgeon
What Our Patients Say
Discover the experiences of those who have walked through our doors by exploring verified patient reviews from Google Business. Click the names to see the original reviews.
I would like to express my deepest gratitude to Dr. Cem and his team for the exceptional care I received during my surgery in Turkey this past January. Every aspect of the experience was managed with remarkable professionalism, attentiveness, and organization, which made me feel well cared for from the very beginning. Ozlem was outstanding throughout the entire process. She was thorough, attentive, and consistently responsive, ensuring that I was never left uncertain about what to expect. I was always given clear guidance regarding where I needed to be, when things would take place, and how each part of the process would unfold. That level of communication and support was invaluable. The hotel accommodations were also excellent. The hotel was clean, comfortable, and welcoming, which made our stay all the more enjoyable and contributed positively to the overall experience. I am now three months post-operative after an upper blepharoplasty, a cheek lift (oka DPVL), and a lip lift, and I could not be more pleased with how beautifully everything has healed. The result is exactly what I had hoped for: I look like a fresher, more youthful version of myself, not like a different person. That balance is incredibly important, and Dr. Cem achieved it beautifully. He is also a gifted communicator who takes the time to understand his patients’ goals with great care. It is clear that he combines technical precision with a genuine artistic eye, and that combination is reflected in the natural, elegant result he delivers. Equally important to me was his honesty regarding recovery. He never overstated or romanticized the healing process, and everything progressed exactly as he had explained. That honesty gave me enormous confidence and made the entire experience feel grounded, trustworthy, and reassuring. I am truly grateful to Dr. Cem, Ozlem, and the entire team for the wonderful care I received and for making what could have felt overwhelming instead feel smooth, thoughtful, and exceptionally well managed. I am very glad I found Dr. Cem, and I confident know without hesitation, who I would return to should I ever decide to have a neck lift in the future. Thank you!

Happy Golucky
I had a submentoplasty with Dr Cem Berkay three weeks ago, and I couldn't be happier with my experience and results. The procedure was performed in an office setting under local anaesthetic, which made the whole process much calmer and more comfortable than I expected. Dr Berkay did an incredible job—the surgery was flawless, and even with some minor swelling still present, the results are already unbelievable. His assistant, Ozlem, was wonderful from the very beginning—always kind, courteous, and incredibly helpful throughout the entire process. Nurse Volkan was also fantastic, providing reassurance and support during the procedure and making me feel completely at ease. I highly recommend Dr Cem Berkay and his team to anyone considering this procedure. Their professionalism, care, and attention to detail have been exceptional. I could not be happier with the outcome.

Scott
Amazing! He's a doctor with a very high level of knowledge, a great aesthetic sense and skill, and truly attentive to his work 👏 A doctor who can perform such complex surgeries with such composure and professionalism must be very confident. It's a friendly environment where you can also stop by for coffee. He's a legend! I suggest you catch him before he becomes even more unattainable. Thank you, dear Cem Berkay Sınacı 🙏🏻

Gülşah Başandaç
I had a great experience with Dr Cem Berkay Sinaci and his team. He was very attentive to what kind of result I wanted, and also offered his best advice from his experience which I appreciated. I am now 6 months post op, and am super happy with my results. I have had 0 problems but I know I can always reach out to the team if a question or concern did arise. I would definitely recommend Dr Cem Berkay Sinaci clinic for your future surgery

Ieva Svara
Dr. Cem has been a dear friend of mine for almost 20 years, and I didn't hesitate for a second to choose him for my rhinoplasty and midface lift through lower blepharoplasty. Having witnessed his exceptional work over the years, I knew I was in good hands. As expected, the entire process was smooth and seamless. It's been a month now, and while I still have some edema, it's well within the normal range. Remarkably, I had no bruising after just one week. I always believed Dr. Cem's patients were fortunate, and now I am proud to count myself among them. Thank you, Dr. Cem, for everything. P.S. My mother also had an upper blepharoplasty with him a few months ago. She too is immensely grateful and says he is an excellent surgeon.

Serkan Haslak
Dr. Cem is such a caring and professional doctor that I realized this during my first operation, after visiting countless doctors and coming to him through Dr. Nuray's recommendation. My family trusted him as much as I did, and he never let us down. I definitely recommend him. He is absolutely the best doctor you can go to in his field :)

Ece Kader
What Our Patients Say
Discover the experiences of those who have walked through our doors by exploring verified patient reviews from Google Business. Click the names to see the original reviews.
I would like to express my deepest gratitude to Dr. Cem and his team for the exceptional care I received during my surgery in Turkey this past January. Every aspect of the experience was managed with remarkable professionalism, attentiveness, and organization, which made me feel well cared for from the very beginning. Ozlem was outstanding throughout the entire process. She was thorough, attentive, and consistently responsive, ensuring that I was never left uncertain about what to expect. I was always given clear guidance regarding where I needed to be, when things would take place, and how each part of the process would unfold. That level of communication and support was invaluable. The hotel accommodations were also excellent. The hotel was clean, comfortable, and welcoming, which made our stay all the more enjoyable and contributed positively to the overall experience. I am now three months post-operative after an upper blepharoplasty, a cheek lift (oka DPVL), and a lip lift, and I could not be more pleased with how beautifully everything has healed. The result is exactly what I had hoped for: I look like a fresher, more youthful version of myself, not like a different person. That balance is incredibly important, and Dr. Cem achieved it beautifully. He is also a gifted communicator who takes the time to understand his patients’ goals with great care. It is clear that he combines technical precision with a genuine artistic eye, and that combination is reflected in the natural, elegant result he delivers. Equally important to me was his honesty regarding recovery. He never overstated or romanticized the healing process, and everything progressed exactly as he had explained. That honesty gave me enormous confidence and made the entire experience feel grounded, trustworthy, and reassuring. I am truly grateful to Dr. Cem, Ozlem, and the entire team for the wonderful care I received and for making what could have felt overwhelming instead feel smooth, thoughtful, and exceptionally well managed. I am very glad I found Dr. Cem, and I confident know without hesitation, who I would return to should I ever decide to have a neck lift in the future. Thank you!

Happy Golucky
I had a submentoplasty with Dr Cem Berkay three weeks ago, and I couldn't be happier with my experience and results. The procedure was performed in an office setting under local anaesthetic, which made the whole process much calmer and more comfortable than I expected. Dr Berkay did an incredible job—the surgery was flawless, and even with some minor swelling still present, the results are already unbelievable. His assistant, Ozlem, was wonderful from the very beginning—always kind, courteous, and incredibly helpful throughout the entire process. Nurse Volkan was also fantastic, providing reassurance and support during the procedure and making me feel completely at ease. I highly recommend Dr Cem Berkay and his team to anyone considering this procedure. Their professionalism, care, and attention to detail have been exceptional. I could not be happier with the outcome.

Scott
Amazing! He's a doctor with a very high level of knowledge, a great aesthetic sense and skill, and truly attentive to his work 👏 A doctor who can perform such complex surgeries with such composure and professionalism must be very confident. It's a friendly environment where you can also stop by for coffee. He's a legend! I suggest you catch him before he becomes even more unattainable. Thank you, dear Cem Berkay Sınacı 🙏🏻

Gülşah Başandaç
I had a great experience with Dr Cem Berkay Sinaci and his team. He was very attentive to what kind of result I wanted, and also offered his best advice from his experience which I appreciated. I am now 6 months post op, and am super happy with my results. I have had 0 problems but I know I can always reach out to the team if a question or concern did arise. I would definitely recommend Dr Cem Berkay Sinaci clinic for your future surgery

Ieva Svara
Dr. Cem has been a dear friend of mine for almost 20 years, and I didn't hesitate for a second to choose him for my rhinoplasty and midface lift through lower blepharoplasty. Having witnessed his exceptional work over the years, I knew I was in good hands. As expected, the entire process was smooth and seamless. It's been a month now, and while I still have some edema, it's well within the normal range. Remarkably, I had no bruising after just one week. I always believed Dr. Cem's patients were fortunate, and now I am proud to count myself among them. Thank you, Dr. Cem, for everything. P.S. My mother also had an upper blepharoplasty with him a few months ago. She too is immensely grateful and says he is an excellent surgeon.

Serkan Haslak
Dr. Cem is such a caring and professional doctor that I realized this during my first operation, after visiting countless doctors and coming to him through Dr. Nuray's recommendation. My family trusted him as much as I did, and he never let us down. I definitely recommend him. He is absolutely the best doctor you can go to in his field :)

Ece Kader
What Our Patients Say
Discover the experiences of those who have walked through our doors by exploring verified patient reviews from Google Business. Click the names to see the original reviews.
I would like to express my deepest gratitude to Dr. Cem and his team for the exceptional care I received during my surgery in Turkey this past January. Every aspect of the experience was managed with remarkable professionalism, attentiveness, and organization, which made me feel well cared for from the very beginning. Ozlem was outstanding throughout the entire process. She was thorough, attentive, and consistently responsive, ensuring that I was never left uncertain about what to expect. I was always given clear guidance regarding where I needed to be, when things would take place, and how each part of the process would unfold. That level of communication and support was invaluable. The hotel accommodations were also excellent. The hotel was clean, comfortable, and welcoming, which made our stay all the more enjoyable and contributed positively to the overall experience. I am now three months post-operative after an upper blepharoplasty, a cheek lift (oka DPVL), and a lip lift, and I could not be more pleased with how beautifully everything has healed. The result is exactly what I had hoped for: I look like a fresher, more youthful version of myself, not like a different person. That balance is incredibly important, and Dr. Cem achieved it beautifully. He is also a gifted communicator who takes the time to understand his patients’ goals with great care. It is clear that he combines technical precision with a genuine artistic eye, and that combination is reflected in the natural, elegant result he delivers. Equally important to me was his honesty regarding recovery. He never overstated or romanticized the healing process, and everything progressed exactly as he had explained. That honesty gave me enormous confidence and made the entire experience feel grounded, trustworthy, and reassuring. I am truly grateful to Dr. Cem, Ozlem, and the entire team for the wonderful care I received and for making what could have felt overwhelming instead feel smooth, thoughtful, and exceptionally well managed. I am very glad I found Dr. Cem, and I confident know without hesitation, who I would return to should I ever decide to have a neck lift in the future. Thank you!

Happy Golucky
I had a submentoplasty with Dr Cem Berkay three weeks ago, and I couldn't be happier with my experience and results. The procedure was performed in an office setting under local anaesthetic, which made the whole process much calmer and more comfortable than I expected. Dr Berkay did an incredible job—the surgery was flawless, and even with some minor swelling still present, the results are already unbelievable. His assistant, Ozlem, was wonderful from the very beginning—always kind, courteous, and incredibly helpful throughout the entire process. Nurse Volkan was also fantastic, providing reassurance and support during the procedure and making me feel completely at ease. I highly recommend Dr Cem Berkay and his team to anyone considering this procedure. Their professionalism, care, and attention to detail have been exceptional. I could not be happier with the outcome.

Scott
Amazing! He's a doctor with a very high level of knowledge, a great aesthetic sense and skill, and truly attentive to his work 👏 A doctor who can perform such complex surgeries with such composure and professionalism must be very confident. It's a friendly environment where you can also stop by for coffee. He's a legend! I suggest you catch him before he becomes even more unattainable. Thank you, dear Cem Berkay Sınacı 🙏🏻

Gülşah Başandaç
I had a great experience with Dr Cem Berkay Sinaci and his team. He was very attentive to what kind of result I wanted, and also offered his best advice from his experience which I appreciated. I am now 6 months post op, and am super happy with my results. I have had 0 problems but I know I can always reach out to the team if a question or concern did arise. I would definitely recommend Dr Cem Berkay Sinaci clinic for your future surgery

Ieva Svara
Dr. Cem has been a dear friend of mine for almost 20 years, and I didn't hesitate for a second to choose him for my rhinoplasty and midface lift through lower blepharoplasty. Having witnessed his exceptional work over the years, I knew I was in good hands. As expected, the entire process was smooth and seamless. It's been a month now, and while I still have some edema, it's well within the normal range. Remarkably, I had no bruising after just one week. I always believed Dr. Cem's patients were fortunate, and now I am proud to count myself among them. Thank you, Dr. Cem, for everything. P.S. My mother also had an upper blepharoplasty with him a few months ago. She too is immensely grateful and says he is an excellent surgeon.

Serkan Haslak
Dr. Cem is such a caring and professional doctor that I realized this during my first operation, after visiting countless doctors and coming to him through Dr. Nuray's recommendation. My family trusted him as much as I did, and he never let us down. I definitely recommend him. He is absolutely the best doctor you can go to in his field :)

Ece Kader
For International Patients
You can read our details who will come from abroad

For International Patients
You can read our details who will come from abroad

For International Patients
You can read our details who will come from abroad

Related Posts
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Schedule Your Consultation
International patients can arrange a detailed video consultation to discuss their goals. For patients in Istanbul, we welcome you to our clinic for an in-person evaluation. Your journey begins with understanding your unique needs.
Schedule Your Consultation
Begin your journey to a more confident you.
Schedule Your Consultation
Begin your journey to a more confident you.
Schedule Your Consultation
Begin your journey to a more confident you.
Dr. CBS, European and Turkish Board-certified plastic, reconstructive, and aesthetic surgeon in Istanbul
Face & Neck
Breast & Body
Non-surgical
Copyright © 2026 Dr. Cem Berkay Sınacı. All Rights Reserved
Dr. CBS, European and Turkish Board-certified plastic, reconstructive, and aesthetic surgeon in Istanbul
Face & Neck
Breast & Body
Non-surgical
Copyright © 2026 Dr. Cem Berkay Sınacı. All Rights Reserved
Dr. CBS, European and Turkish Board-certified plastic, reconstructive, and aesthetic surgeon in Istanbul
Face & Neck
Breast & Body
Non-surgical
Copyright © 2026 Dr. Cem Berkay Sınacı. All Rights Reserved




